Surviving AAI's

There are MANY NEW Clinical Trials out there for RA and much more. "Cure Click" is helping to make the possibility of you participating in a Clinical Trial a better less stressful as far as red tape and paperwork!!!

Please visit the information and URL's below!!! 

http://community.cureclick.com/rheumatoid-arthritis-clinical-trial/?utm_source=cureclick&utm_medium=email&utm_campaign=weekly_newsletter_2#prettyPhoto

Rheumatoid Arthritis Clinical Trial

The currently recruiting trial listed on CureClick for rheumatoid arthritis is a clinical study for a biosimilar medication. We have received several messages about this trial so we wanted to post some additional information:

According to the FDA, “Biosimilars are a type of biological product that are licensed (approved) by FDA because they are highly similar to an already FDA-approved biological product, known as the biological reference product (reference product), and have been shown to have no clinically meaningful differences from the reference product.” 

For this trial, one group will be given the currently approved and available medication Rituxan® (rituximab) and the other will be on a biosimilar version of rituxumab. Neither group will receive a placebo. The goal of the trial is to see if the study drug is as safe and effective in patients with rheumatoid arthritis and attempt to show it has no clinically meaningful difference to the reference product (Rituxan®).

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MORE ABOUT THE STUDY FROM THE SPONSOR:

The purpose of this study is to compare the proposed biosimilar study drug rituximab (GP2013) against a standard approved treatment rituximab (Rituxan®) to see if the study drug is as safe and effective in patients with rheumatoid arthritis.

• The study drug (GP2013 and Rituximab) is administered by IV Injection (IV).
• At least 174 people have already taken this drug in clinical trials
• All study related medications, analysis, hospital visits and procedures are free

Eligibility Criteria:

Participants must:

• be at least 18 years old
• have been diagnosed with rheumatoid arthritis for at least 6 months
• have had inadequate response or intolerance to DMARDs (disease-modifying anti-rheumatic drugs) and 1 – 3 anti-TNF (tumor necrosis factor) therapies
• have received methotrexate for at least 4 months with 25 mg/week as the maximal dose

Participants must not:

• have significant liver disease, or congestive heart failure
• be taking a high potency of opioid analgesics (e.g. methadone, hydromorphone, morphine)

For more information about the study, please visit the link provided to you by _______________________________________your Ambassador.

My "Illnesses, Surgeries, and Medications"

When I begin to see others about my "illnesses" , the many surgeries I have endured, and the number of medications it takes to keep my body in a state of somewhat "normality", even Doctors and Nurses have gone into a state of "shock".

Illnesses: Lupus, Mixed Connective Tissue Disorder, Rheumatoid Arthritis, Sjogren's, Severe Osteoporosis, 2 Myocardial Infarctions (1 heart attack at age 40 and the 2nd at age 50), High Blood Pressure, "probable" Multiple Sclerosis, Chronic Pain Syndrome, Degenerative Joint and Disc Disease,B-12 Deficiency (Pernicious Anemia), Chronic Double Vision, Chronic Vertigo, Menieres Disease, Chronic Migraines, Kidney Stones (and I probably left something out)

Surgeries: 2 Total Knee Replacements (after at least 2 arthroscopies on each knee), Right Total Reverse Shoulder Replacement, 2 other arthroscopies on both both shoulders, a 4 level Cervical Discectomy/Fusion, an Internally Implanted Pain Pump, Gallbladder Removed, Hysterectomy, Bladder SurgeryLeft Elbow Surgery, Left Carpal Tunnel Release Surgery, Temporal Artery Biopsy & once again I have probably left something out.

Medications: Methotrexate, Plaquenil, Orencia (Once a Week Self Injection), Lisonpril, Pravastin, Prednisone, Forteo(daily injection), Lasix, Valium, Robaxin, Meclazine, BC Powders, Folic Acid, Nexium, Promethazine, B-12 - 1 injection monthly, B-12 tablet daily,Nystatin and Lidocaine (for oral mouth ulcers, sore throats), Carafate, Singular, Metropolol, Ranexa, Sulfasalazine, Multi-Vitamin & I once every 3 months I have to go in and have my pain pump refilled, plus there is probably something I am forgetting.

This does not even account for some of the other illnesses/issues/symptoms caused from not only these illnesses, BUT also from the medications I take. things such a quick deterioration of your teeth from Sjogren's due to the lack of moisture from your mucus members. Fatigue, Stiffness, Pain Chronic, Severe Mouth Ulcers and sore throats, Lupus Migraines, skin thinning, hair thinning, the "Lupus Mask" over the cheeks and nose. (by the way, an interesting fact… Lupus means "Wolf". The illness became named this due to the "reddish brown mask on the cheeks and nose that almost looks like a mask on a Wolf's face).